BM163575
BIO-X

MCC 950 sodium NEW

Inhibitor of NLRP3 inflammasome and suppressor of the inflammatory cytokine IL-1β secretion. The compound was tested in diabetic mice and was shown to decrease the incidence of cardiac arrythmias, which are common secondary complications in diabetes mellitus. MCC 950 has potential to reverse diabetes-induced pathologies in cardiac electrophysiology.


Technical Data

CAS号: 256373-96-3
别名: N-​[[(1,​2,​3,​5,​6,​7-​Hexahydro-​s-​indacen-​4-​yl)​amino]​carbonyl]​-​4-​(1-​hydroxy-​1-​methylethyl)​-2-​furansulfonamide sodium; CP-456773 sodium; CRID3 sodium
产品编码: BM163575
分子式: C20H23N2O5S·Na
分子量: 426.46

References

参考文献
  • Monnerat et al (2016). Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice. Nature Communications 7:1334.

Solubility

Stability

Further Information


Datasheets

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