1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride1-乙基-(3-二甲基氨基丙基)碳酰二亚胺盐酸盐

Commonly known as EDAC, EDC or EDCI, this carbodiimide HCl salt is used as a coupling reagent in the synthesis of amides and carboxylic esters. EDAC is highly soluble in water and in most organic solvents, it can be employed in liquid and solid-phase and synthesis. The major advantage of EDCI over other carbodiimides such as DCC and DIC is the ease of purification of the product from the water-soluble urea by-product by washing the crude mixture with water or mild acid and extracting in the organic phase. The main applications of EDAC are in peptide synthesis, Steglich esterification reactions in presence of catalytic DMAP, immunoconjugate synthesis, synthesis of sulfo-NHS esters and coupling of biomolecules onto solid supports.

Technical Data

CAS号: 25952-53-8
别名: EDC.HCl; EDAC.HCl; Water Soluble Carbodiimide; N-Ethyl-N'-(3-dimethylaminopropyl)carbodiimide HCl; 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide HCl
产品编码: FD05800
MDL号: MFCD00012503
分子式: C8H18ClN3
分子量: 191.7 g/mol


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Further Information


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